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KMID : 0357919780120010000
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Korean Journal of Pathology
1978 Volume.12 No. 1 p.0 ~ p.47
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Incidence of HBsAg Positivity and Liver Function Tests in Leprosy Patients
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정상우(鄭相愚)/S.W. Juhng
양동욱(梁東旭)/유주용(柳柱容)/김상호(金象皓)/조규혁(曺圭赫)/D.W. Ryang/J.Y.Yoo/S.H. Kim/K.H. Cho
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Abstract
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Hepatitis B surface antigen and liver function tests were carried out to evaluate the
degree of hepatic damage in 147 leprosy patients admitted in Sorok National
Leprosarium. In 147 leprosy patients, 118 were of a lepromatous type, 16 were of a
tuberculoid type and 13 were of a borderline group.
The results were obtained as follows;
1. In leprosy patients, HBsAg positivity was observed in 4(2.7%) lepers, which was
lower than 4(4%) positivity in normal control group.
2. The abnormal elevations of serum alkaline phosphatase, SGOT, SGPT and 777 were
observed in 37(25.2%), 24(16.3%), 12(8.2%) and 20(13.5%) lepers respectively. Inverted
A/G ratio was noticed in 28(19.0%) lepers.
These data of various liver function tests except for SGPT tests in leprosy patients
were statistically significant.
3. The abnormal elevations of serum alkaline phoshatase were chiefly observed in the
lepers below age of 20 years, in borderline group and in the group of treatment with
rifampin.
The abnormal elevations of SGOT and inverted A/G ratio seemed to be increased
with duration of illness and treatment.
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